i got a C note that says you won't gain any measurable efficiency gain, however
i am not putting a dime on a bet until such time as i see how you will be testing before and after, "and" until such time as there are others that can independently verify those results, preferably by independent replication.
before anything is done to the ports there is a lot of work that needs to be done in setting up a suitable test cell, followed by several tests to determine a baseline.
do that first and get some agreement as to the methods used to test, then go after the porting.
you might set a goal of maybe 1 to 2 percentage points in efficiency gains as being about the maximum gains you are going to accomplish under any circumstances via porting alone... setting up suitable test capability to measure 1 to 2 percentage points "reliably" is going to be quite an accomplishment to start with let alone trying to improve things via porting.
bob g
ps
you might consider this,
if you are looking for more power, or more efficiency or both...
replace the flywheels with stover wheels and crank the rpm up to closer to 1000rpm... you might have to replace the iron piston as well. enclose the cooling system and make it a pressurized system running at ~220deg F under load... doing these things will net you a couple points increase in efficiency... "and" then worry about porting... maybe then you might see a slight improvement but i would not bet on it.
the problem with the 6/1 is there is a massive amount of iron that sucks the heat away from the combustion process. lost heat does not make for more power as we all know... added to the problem is the very slow rpm and you have a lot of time for this heat to flow away from the combustion process... the two together limit the engine's ability to be much more efficient than it already is. anything you can do to reduce the heat flow either by raising the cooling system temperature or decreasing the dwell time via increased rpm is a step in the right direction.
in my opinion the lister design as with any design is one of compromise(s) they wanted a slow speed engine to increase longevity, lots of iron to make it more stable, simple so that anyone can work on it, etc... balancing that against efficiency.
with the cost of fuel being pennies per gallon back at the 5/1's inception, it is really doubtful that eeking out the highest efficiency was very high on the list of priorities. if the design was so damn good they would not have gone on to design and manufacture more advanced designs in more recent times.